Tianeptine is a medication that is said to help relieve anxiety and treat depression. People use it to improve their symptoms of depression and to even treat their asthma.
However, tianeptine isn’t without its controversies. Unfortunately, there is a lot of misinformation out there with regards to this drug. Thankfully, we’ve done the research and have the facts.
So if you are looking to learn more about tianeptine, then you have come to the right place. Keep on reading and we will walk you through everything that you will want to know about tianeptine.
What Is Tianeptine?
Tianeptine is a medication that is mainly used to improve symptoms of MDD (major depressive disorder). It’s also been used to treat asthma and even IBS (irritable bowel syndrome).
The drug has both anti-anxiety and antidepressant qualities. It has a variety of effects on the human body. These effects include:
- cognitive fatigue
- rejuvenation
- focus enhancement
- cognitive euphoria
- anxiety suppression
- motivation enhancement
The drug was first patented and discovered in the 1960s by the French Society of Medical Research. The brand names for tianeptine include Salymbra, Tianeurax, Tatinol, Coaxil, and Stablon.
The drug is available in some countries in South America, Asia, and Europe. However, the drug is banned in the United Kingdom. It is also not medically prescribed in the United States of America by doctors.
The monoaminergic hypothesis of depression has been challenged by tianeptine. The same is true for the proposed monoaminergic mechanisms in which the action of most modern antidepressants was explained.
With that said, no one is actually totally sure how tianeptine helps the conditions that have been listed or even how it really works.
The mechanisms that are listed are possible mechanisms by which it can help these conditions.
Proposed Mechanisms for Tianeptine in Depression
There are several proposed mechanisms for tianeptine in depression. Let’s go over the most common ones below.
First, it is believed that tianeptine modulates the glutamate receptors, including AMPA and NMDA receptors. It also might normalize glutamate levels.
By enhancing the reuptake of serotonin, the tianeptine can help to soak up serotonin from outside of the cell. This will lead to more serotonin inside of the cell.
Uses of Tianeptine
In the jurisdictions where the drug is approved, it is mainly used for anxiety and depression disorders. However, some doctors might prescribe tianeptine for other issues, such as IBS and asthma.
If your doctor prescribes this drug to you, you need to make sure that you follow the treatment regimen very carefully.
You never want to change the dose or stop taking the medication unless you consult your doctor about it first.
Depressive Symptoms
Tianeptine is often as effective as a lot of traditional antidepressants in people who have adjustment disorder, dysthymia, and major depressive disorder. Also, extended treatment with tianeptine will likely reduce the chances of recurrence and relapse of depression.
Tianeptine can decrease the intensity of depression. It can also improve a person’s quality of life.
For people who suffer from Parkinson’s disease, the drug can also be extremely helpful. It can even help with memory and learning impairment and seizures. This means that it can be beneficial to people who have epilepsy.
Tianeptine might have more potential for people in certain groups who have depression, such as those with alcohol addiction and the elderly. This is because it has a relative lack of cardiovascular, anticholinergic, and sedative adverse effects.
It might decrease appetite and help with depressive symptoms in postmenopausal women too. However, it shouldn’t be used to treat obesity because it won’t affect a person’s weight in the long run.
PTSD, Stress, and Anxiety Symptoms
Tianeptine can improve symptoms of anxiety and can boost neurocognitive functions. It can also reduce a person’s reaction to panic.
The drug also has memory-protective properties. This is because it can block the negative effects of stress on hippocampus-dependent memory and learning.
Asthma
When you experience an asthma attack, free serotonin and catecholamines will be found circulating in your blood. Tianeptine is able to decrease free serotonin in the blood. It is able to do this by enhancing serotonin uptake of serotonergic brain cells and platelets.
When free serotonin is taken up by lung cells, it can induce bronchial contraction. Treatment with tianeptine can provoke a quick cessation of asthma attacks.
The drug can also reduce free serotonin levels and improve lung function.
Irritable Bowel Syndrome
Serotonin has a big role in the nervous system of the intestinal tract. Here, it is able to control the movement of digestive material and intestinal secretions.
When you have increased serotonin, you will end up with elevated movement and secretions. This can lead to diarrhea, bloating, and pain in people who have irritable bowel syndrome (IBS).
When you take tianeptine, you can decrease the amount of serotonergic activity and then improve symptoms that are associated with irritable bowel syndrome.
Don’t forget to check out this page for more information on the benefits and uses of tianeptine.
The Importance of Knowing About Tianeptine
Hopefully, after reading the above article, you now have a better idea of what tianeptine is and how it works. As we can see, it has the potential to bring a lot of benefits to a lot of people. Make sure to ask your doctor to see if tianeptine can help you.
Don’t forget to check out the rest of our blog today for more helpful articles!